<em>Sistine Madonna</em> is an oil painting by the Italian artist Raphael. Commissioned in 1512 by Pope Julius II as an altarpiece for the church of San Sisto, Piacenza, it was one of the last Madonnas painted by the artist. Relocated to Dresden from 1754, the well-known painting has been particularly influential in Germany. The painting has been highly praised by many notable critics, and Giorgio Vasari called it a "a truly rare and extraordinary work".